心血管

  • heart
    • Location
      • In the mediastinum
        • Between the lungs
        • Mediastinum 纵隔 is a region that extends from sternum to vertebral column and from 1st rib to diaphragm
      • 2/3 of the mass of the heart lies to the left of the body’s midline.
      • Visualizes as a cone lying on its side
    • 外观
      • Apex
        • formed by the tip of LV and rests on the diaphragm
        • directed anteriorly, inferiorly, and to the left
      • Base
        • opposite the apex
        • formed by the atria, mostly the LA
      • Anterior surface
        • deep to the sternum and ribs
      • Inferior/diaphragmatic surface
        • rests on the diaphragm
      • Right surface
        • faces the right lung
      • Left surface
        • faces the left lung
      • Auricle 心耳
        • resembles a dog’s ear
        • on the anterior surface of each atrium
      • Sulci
        • a series of grooves沟 on heart surface
        • contain coronary blood vessels and fat
        • external boundary for 4 chambers
          • coronary sulcus 冠状沟
            • 分隔 atria and ventricles
          • anterior interventricular sulcus 前室间沟
            • 分隔 RV and LV on the anterior surface
          • posterior interventricular sulcus 后室间沟
            • 分隔 RV and LV on the posterior surface
    • Right atrium
      • Entry
        • Superior vena cava
        • Inferior vena cava
        • Coronary sinus 冠状窦
          • opening of deoxygenated blood from the myocardium
      • Exit
        • Tricuspid valve
      • 结构
        • Smooth posterior wall of the inner layer
        • Rough anterior wall of the inner layer due to pectinate muscles 梳状肌//左边掀起来的
        • Pectinate muscles extend into the auricle
        • Interatrial septum (septum = a dividing wall)
        • fossa ovalis - oval depression 卵圆窝
    • Right ventricle
      • Exit
        • pulmonary valve into pulmonary trunk 肺动脉干
        • pulmonary trunk divides into right and left pulmonary arteries
      • 结构
        • forms most of the anterior surface of the heart
        • inside of the RV contains trabeculae carneae 肉柱
        • cusps of the tricuspid valve connect to chordae tendineae 腱索
        • chordae tendineae connect to papillary muscles 乳头肌
        • RV separated from LV by interventricular septum
    • Operation of tricuspid and bicuspid
      • ventricles relax → papillary muscles relax → chordae tendineae are slack → blood flows from a higher pressure in the atria to a lower pressure in the ventricles through open valves
      • ventricles contract → pressure of the blood drives the cusps upward and close the opening → papillary muscles contract → pulls on chordae tendineae → prevents the backflow of blood
    • Left atrium
      • Entry
        • four pulmonary veins
      • Exit
        • bicuspid valve
      • forms most of the base of the heart
      • smooth inner layer as pectinate muscles only in the auricle of the LA
      • 后面看, 左右肺静脉流入左心房
    • Left ventricle
      • Thickest chamber
      • Forms the apex of the heart
      • Contains trabeculae carneae and chordae tendineae
      • Exit
        • aortic valve into the ascending aorta
          • ascending aorta
          • arch of the aorta
          • descending aorta (thoracic aorta and abdominal aorta)
      • ligamentum arteriosum 动脉韧带 connects the pulmonary trunk and the aorta
    • Fibrous rings
      • Four dense connective tissue rings surround the valves of the heart
      • form a structural foundation for the heart valves
      • prevent overstretching of the valves as blood passes through them
      • acts as an electrical insulator between the atria and ventricles
  • conduction sysytem
    • Autorhythmic fibers - specialized cardiac muscle fibers
    • Self-excitable - act as a pacemaker, generate AP
    • Cardiac chambers contract in a coordinated manner
    • 兴奋过程
      • Cardiac excitation begins in the sinoatrial node
      • AP propagates through both atria via intercalated discs
      • Both atria contract
      • AP reaches the atrioventricular node
      • AP enters the atrioventricular bundle 房室束(希氏束)
      • AP enters both the right and left bundle branches 右束支和左束支
      • AP propagates along Purkinje fibers
      • Both ventricles contract
  • Coronary Circulation
    • Coronary arteries
      • branch from the ascending aorta
      • supply oxygenated blood to the myocardium
      • left coronary artery - passes inferior to the left auricle
      • right coronary artery - passes inferior to the right auricle
    • Left coronary artery
      • passes inferior to the left auricle and divides into
        • Left anterior descending (LAD)
          • in the anterior interventricular sulcus 走行于前室间沟内
          • supplies both ventricles
        • Circumflex branch 旋支
          • in the coronary sulcus 走行于冠状沟内
          • supplies both atria
    • Right coronary artery
      • passes inferior to the right auricle and divides into
        • marginal branch 右缘支
          • runs along the right margin of the heart 走行于心脏右缘
          • supplies RV
        • posterior descending of right coronary A 后降支
          • in the posterior interventricular sulcus 走行于后室间沟
          • supplies both ventricles
  • Pericardium
    • Pericardium is triple-layered membrane that surrounds the heart
    • 分为
      • the fibrous pericardium 纤维性心包
        • 在浆膜性心包外面
      • the serous pericardium 浆膜性心包
        • 2层
          • parietal layer
          • visceral layer, AKA epicardium 心外膜
        • pericardial cavity - cavity b/t the parietal and visceral layers 心包腔
        • pericardial fluid - lubricating serous fluid 心包液
  • Heart Wall
    • Epicardium (external layer)
    • Myocardium (middle layer)
      • composed of cardiac muscle tissue
      • makes up approximately 95% of the heart wall
      • responsible for the pumping action
    • Endocardium (inner layer)
      • thin layer of connective tissue
      • minimizes the surface friction as blood passes through the heart
  • Aorta
    • Ascending aorta
      • locates posterior to the pulmonary trunk
      • gives off 2 coronary arteries
      • arches to the left
    • Arch of the aorta
      • 左右在刚开始不相同分支
        • brachiocephalic trunk
          • right common carotid A
          • right subclavian A
          • right vertebral A
            • 横突孔在颈椎上
        • left common carotid
        • left subclavian
          • left vertebral
        • 先分成三个分支
      • 在后面左右对称
        • Common carotid A
          • Ascending aorta → brachiocephalic trunk → right common carotid
          • Ascending aorta → left common carotid
          • Carotid sheath颈动脉鞘 contains the common carotid A, internal jugular V, and vagus N.
          • common carotid A在颈动脉窦部分分成internal carotid A与external carotid A
          • pressure-monitoring receptors in the carotid sinus 颈动脉窦
          • chemoreceptors (receptors that monitor blood levels of oxygen and carbon dioxide) in the carotid bodies 颈动脉小球
          • 分叉的点在喉结高度的地方
        • Arteries of the upper limbs
          • Subclavian A
          • Axillary A 腋动脉
          • Brachial A 肱动脉
          • Radial A 桡动脉
          • Ulnar A 尺动脉
          • Deep palmar arch 掌深弓
          • Superficial palmar arch 掌浅弓
          • 左右对称
    • Descending aorta
      • Thoracic aorta
        • Parietal branches 壁支
          • Posterior intercostal A (9 pairs) 肋间后动脉
            • arise from posterolateral aspect of thoracic aorta
            • Start inferior to 3rd rib
            • run through intercostal space
            • supply intercostal and chest muscles
          • Subcostal A (1 pair) 肋下动脉
            • inferior to 12th rib
            • supply upper abdominal muscles
          • Superior phrenic A (1 pair) 膈上动脉
            • supply diaphragm
        • Visceral branches 脏支
          • Bronchials 支气管支
          • Esophageals 食管支
          • Pericardials 心包支
      • Abdominal aorta
        • Unpaired visceral branches
          • Celiac trunk 腹腔干
              1. Splenic artery
              1. Common hepatic artery
              1. Left gastric artery
            • 没胃
            • 有胃
          • Superior mesenteric A 肠系膜上动脉
            • between pancreas and duodenum
            • supplies from duodenum to transverse colon
          • Inferior mesenteric A 肠系膜下动脉
            • Inferior to duodenum
            • supplies from transverse colon to rectum
        • Paired visceral branches
          • Middle suprarenal A 肾上腺中动脉
          • Renal A 肾动脉
          • Testicular A/Ovarian A 睾丸、卵巢动脉
        • Unpaired parietal branch
          • Median sacral A 骶正中动脉
        • Paired parietal branch
          • Inferior phrenic A (1 pair) 膈下动脉
          • Lumbar A (4 pairs) 腰动脉
      • Arteries of the pelvis and lower limbs
        • right and left common iliac A
          • internal iliac A
          • external iliac A
            • femoral A
            • popliteal A 腘动脉
            • anterior and posterior tibial A 胫前动脉和胫后动脉
        • Femoral triangle
          • SAIL - Sartorius + Adductor longus 长收肌+ Inguinal Ligament 腹股沟韧带
          • 这个区域有动脉, 静脉, 神经
  • Pulmonary circulation
    • deoxygenated blood
      • RV → pulmonary trunk →
        • right pulmonary artery → right lung
        • left pulmonary artery → left lung
    • oxygenated blood
      • ① Left upper lobe
      • ② Left lower lobe
      • ③ Right upper and middle lobe
      • ④ Right lower lobe
  • Veins
    • 基础
      • Venous valves
        • Valve cusps point toward heart
          • allow one-way flow toward the heart
        • Prevent the backflow of blood when muscles relax
      • Mechanisms of venous return
        • Venous return - the flow of blood from the periphery back to the RA
        • Mechanisms
          • Pressure gradient
          • Skeletal muscle pump
          • e.g. contraction of gastrocnemius腓肠肌 prompts venous return
      • Artery vs. Vein
        • 单词的区别
          • Artery 叫 Branch
          • Vein 叫 Tributary - smaller veins draining into larger veins
          • Carotid 颈动脉的
            • Common carotid A
            • External carotid A
            • Internal carotid A
          • Jugular 颈静脉的
            • External jugular V
            • Internal jugular V
        • arteries are deep, veins may be superficial or deep, deep veins go alongside arteries
    • three systemic veins into RA
      • coronary sinus
      • superior vena cava
        • Azygos system
          • Azygos V
            • only on the right side of the vertebral column
            • begins at junction of right ascending lumbar V右腰升静脉 and right subcostal V右肋下静脉 near diaphragm
            • right ascending lumber V 右腰升静脉 is a tributary of common iliac V
            • 穿过diaphragm
          • Hemiazygos V
          • Accessory hemiazygos V
        • Brachiocephalic veins
          • 分为 Right Brachiocephalic veins(3cm) 与 Left Brachiocephalic veins(6cm)
          • Subclavian V + Internal jugular V → brachiocephalic V → superior vena cava 都由两个静脉汇入
          • Subclavian V
            • 位置
              • inferior to minor pectoral muscle
              • inferior to clavicle
              • superior to 1st rib
            • External jugular veins 颈外静脉
              • Across sternocleidomastoid 胸锁乳突肌
              • External jugular vein → subclavian V
              • Become very prominent凸显 along side of neck when venous pressure rises
            • Axillary vein 腋静脉
              • 位置
                • Axillary vein → Subclavian V
                • Starts at border of the teres major 大圆肌边缘
                • Ends at subclavian V
              • Veins of the Upper Limbs
                • Deep veins
                  • 特点
                    • Locate deep in the body
                    • Follow the course of the arteries
                    • Two veins accompany one artery
                    • Have the same names as the corresponding arteries
                  • Brachial veins 肱静脉
                    • Two brachial veins
                    • 起点 - cubital fossa
                    • 终点 - distal border of teres major m
                  • Ulnar veins
                  • Radial veins
                  • Deep venous palmar arch
                • Superficial veins
                  • 特点
                    • locate just deep to the skin and are often visible
                    • do not accompany arteries
                  • Basilic vein 贵要静脉
                    • Starts at the dorsal venous network
                    • Courses on the medial side of the forearm
                    • Basilic vein → the brachial V → Axillary vein
                    • 红色这段
                  • Cephalic vein 头静脉
                    • Starts at the dorsal venous network
                    • Courses on the lateral side of the forearm
                    • Cephalic vein → Axillary V
                    • 红色这段
                  • Median cubital vein
                    • Connects cephalic V and basilic V in cubital fossa 肘窝
                    • Commonly used for venipuncture 静脉穿刺
                  • Intercaptitular vein
                  • Dorsal venous network of hand
                    • Venous network on the dorsum of the hand
                    • lateral aspect of dorsal venous network → Cephalic V (radial side of forearm) 头静脉
                    • medial aspect of dorsal venous network → Basilic V (ulnar side of forearm) 贵要静脉
          • Internal jugular V
            • facial vein
              • Ophthalmic V 眼静脉
                • 路径
              • Deep facial V
                • Deep facial V → Pterygoid plexus 翼静脉丛 → Cavernous sinus
              • Cavernous sinus 海绵窦
                • 连着许多静脉,动脉,神经感染会有危险
            • 病-CVC
              • Central Venous Catheter 中心静脉导管
              • IJV是CVC最常见的穿刺部位之一
        • 总结
          • 从手背静脉注射的路径
      • inferior vena cava
        • 基础
          • Blood from abdominal and pelvic viscera returns to inferior vena cava. 下腔静脉的属支
          • Bood from GI tract, spleen, pancreas, and gallbladder return to hepatic portal vein. 肝门静脉系
          • Collects blood from the lower half of the body (below the diaphragm)
          • No valves
          • Starts at the junction of the right and left common iliac V
          • Runs on the right side of the vertebral column
          • Runs on the right of the abdominal aorta
        • Visceral tributaries
          • Hepatic V
          • Left renal V
            • Left suprarenal V
            • Left ovarian/testicular V
          • Right renal V
          • Right suprarenal V
          • Right ovarian/testicular V
        • Parietal tributaries
          • Lumbar V (4 pairs)
          • Inferior phrenic V
        • Veins of the lower limbs
          • 分类
            • Superficial veins
              • In subcutaneous layer
              • Anastomose with one another and with deep veins
              • Do not go with arteries
            • Deep veins
              • Go with arteries
              • Have the same names as corresponding arteries
            • All veins of the lower limbs have valves, which are more numerous than in veins of the upper limbs.
          • Veins of thigh
              1. Femoral V
              • Accompany femoral A
              • Extends from external iliac V at the region of the inguinal ligament 腹股沟韧带
              • Femoral V → external iliac V → common iliac V → inferior vena cava → right atrium
              1. Deep vein of thigh
              • a tributary of femoral V 股深静脉
              1. Popliteal V
              • continuation of femoral V
              • Femoral V goes through adductor hiatus into popliteal V.
            • 紫色Deep vein of thigh,浅蓝色Femoral V
          • Veins of legs
            • Anterior tibial V 胫前静脉
            • Posterior Tibial V 胫后静脉
              • Lies posterior to the medial malleolus in the ankle and ascends 内踝后侧上行
            • Fibular V
              • Lies posterior to the lateral malleolus in the ankle and ascends to empty into the posterior tibial V 外踝后侧上行
          • Superficial veins
            • Great saphenous veins
              • Just deep to skin
              • Begin at medial end of dorsal venous arch
              • Pass anterior to medial malleolus of tibia 内踝前
              • Ascends along medial side of leg and thigh
              • Empty into femoral vein
              • Have 10-20 valves, with more located in leg than thigh
              • Varicose veins: enlarged, twisted veins
              • Longest veins in body
            • Small saphenous V
              • Deep to skin
              • Begin at lateral aspect of dorsal venous arch
              • Ascend along posterior aspect of leg
              • Empty into popliteal V, posterior to knee
              • Have 9-12 valves
            • 足背
              • dorsal digital V → dorsal metatarsal V → dorsal venous arches
              • 外侧Small saphenous V,Begin at lateral aspect of dorsal venous arch足背静脉弓
              • 内侧Great saphenous V,Begin at medial end of dorsal venous arch
          • 总结
        • 总结